You can ask many different experts, and neuroplasticity will be explained in many different ways. In stroke recovery, neuroplasticity basically refers to the ability of the brain to rewire or reorganize itself after injury. Neuroplasticity exercises for stroke recovery require task repetition.
Medically reviewed by Karen Murray, OTR, CHT, CSRS

Various studies over the past decade have shown that the adult brain can "rewire" itself when damaged, creating new neurons, a phenomenon called neurogenesis. These new neurons require support from neighboring cells, blood supply, and connection with other neurons to survive. During rehabilitation, task repetition and task specific practice is needed for neurogenesis and plasticity to change the brain. Hundreds of repetitions per day and thousands over time are needed for these changes according to various research studies.
Since neuroplasticity principles require repetition of task and task specific practice to be effective, the stroke patient should incorporate these techniques in their daily lives. What this means for the stroke patient is that going to see your therapist for a one hour visit (or even a 3 hour visit) is not enough to lead to neuroplastic changes in the brain. Patients need to think of physical, occupational, and speech therapy as an adjunct to stroke recovery. It's up to the patient to make the most of recovery by continuously using the injured parts of the body and mind outside of therapy sessions in everyday life.
A good comparison would be how one learns multiplication. A teacher doesn't just show a multiplication table a couple of times to her students for the concept to be mastered. Instead, students have to practice over and over to learn and master multiplication. A child doesn't learn how to walk overnight. It requires much practice. A baseball player doesn't become elite just by playing a few games of baseball. You must take control of your stroke recovery process and be willing to invest a lot of time and energy if you want to see change especially with moderate to severe stroke. It's also important to keep using a skill once you have mastered it - use it or lose it as you often hear in rehab.
Please note that plasticity doesn't mean that one can practice every task over and over and accomplish them all. Stroke is much more complicated than that. Different parts of the brain control different body functions and the brain adapts better to some areas of damage more than others. Scientists have identified certain areas of the brain that yield neurogenesis but have not identified it in all areas of the brain.
If you want to learn more about your specific stroke, ask your neurologist specifically what areas of your brain were affected. The neurologist will also be able to tell you what problems you can expect because of that damage (e.g. speech deficits, vision deficits, dizziness, difficulties with balance, etc.) You can further improve your rehabilitation by specifically targeting the weaknesses caused by your stroke.
Neuroplasticity principles doesn't necessarily require you to change the type of exercises and therapeutic activities done in stroke rehabilitation but rather emphasizes that more repetition and task specific practice is needed. Probably the most commonly used therapy that is based on neuroplasticity is constraint induced movement therapy (CIMT). CIMT involves limiting the movement of the non-affected or stronger arm and instead using the affected or weaker arm more frequently and intensely.
There has been some positive research results with CIMT, however, it requires much effort and patience from the stroke patient. Some other treatments that may help with brain reorganization include interactive metronome, brain retraining software and websites, mirror box therapy, and robotic and gait devices that assist with movement repetition.
Research is still needed in the area of brain plasticity and stroke rehabilitation. Scientists have demonstrated that brain reorganization can occur and rehab treatments have been developed in attempt to promote neuroplasticity. The stroke patient, armed with the knowledge that brain rewiring occurs with repetition, can improve their rehabilitation outcomes by application of this concept in their daily lives. Remember, therapy is an adjunct to recovery. You cannot go to therapy sessions and expect positive outcomes without applying what you have learned on a consistent daily basis.
Here is a useful infographic on neuroplasticity from NICABM:

Due to brain neuroplasticity, the possibility of improvement — even years after a stroke — is very real. With persistence and repetitive practice, many people continue to make progress. Therapy at a facility a few times per week is not sufficient in making the neuroplastic changes needed, so stroke patients must practice tasks and exercises at home on a daily and regular basis.
If the affected extremities are ignored, this will trigger "learned nonuse". When a stroke patient relies solely on their working side, the brain treats the neglected, affected limb as unnecessary causing the brain to reduce the neural representation area assigned to that limb. This results in a change of the brain's body map, worsening function in the affected extremities.
Lastly, it is important to remember that neuroplasticity has limits. The brain may not always reroute certain kinds of damage, and not all functions can be regained. Research continues to learn more.
Our Stroke Rehab PDF Guide has been developed to help stroke patients perform stroke recovery exercises at homes and has a section dedicated to neuroplasticity, CIMT, and task ideas to help with neuroplastic changes in the brain.

Our comprehensive stroke rehab guide in pdf format is designed for both patients and caregivers who want clear, practical ways to support recovery, improve daily function, and regain independence at home. It includes
A single therapy visit can run $150 or more. The Stroke Rehab Guide is only $14.99, and includes a pdf guide you can continue to refer to in the future with exercises and information on stroke recovery. In addition, any time an update or new version of the guide is written, you will get the updated version for free.

Karen Murray, OTR, CHT, CSRS, is a licensed occupational therapist, Certified Stroke Rehabilitation Specialist, Certified Hand Therapist, and Certified Personal Trainer with over 29 years of experience working with stroke survivors in hospital, outpatient, and home settings. She founded Stroke-Rehab.com to help patients and caregivers better understand stroke recovery, find evidence-based resources, and regain independence at home.
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